Boosting Factual Consistency and High Coverage in Unsupervised Abstractive Summarization

Abstractive summarization has gained attention because of the positive performance of large-scale, pretrained language models. However, models may generate a summary that contains information different from the original document. This phenomenon is particularly critical under the abstractive methods and is known as factual inconsistency. This study proposes an unsupervised abstractive method for improving factual consistency and coverage by adopting reinforcement learning. The proposed framework includes (1) a novel design to maintain factual consistency with an automatic question-answering process between the generated summary and original document, and (2) a novel method of ranking keywords based on word dependency, where keywords are used to examine the coverage of the key information preserved in the summary. The experimental results show that the proposed method outperforms the reinforcement learning baseline on both the evaluations for factual consistency and coverage

HHP1 is involved in osmotic stress sensitivity in Arabidopsis

HHP1 (heptahelical protein 1), a protein with a predicted seven transmembrane domain structure homologous to adiponectin receptors (AdipoRs) and membrane progestin receptors (mPRs), has been characterized. Expression of HHP1 was increased in response to abscisic acid (ABA) and salt/osmotic stress as shown by quantitative real-time PCR and HHP1 promoter-controlled GUS activity. The HHP1 T-DNA insertion mutant (hhp1-1) showed a higher sensitivity to ABA and osmotic stress than the wild-type (WT), as revealed by the germination rate and post-germination growth rate. The induced expression of stress-responsive genes (RD29A, RD29B, ADH1, KIN1, COR15A, and COR47) was more sensitive to exogenous ABA and osmotic stress in hhp1-1 than in the WT. The hypersensitivity in the hhp1-1 mutant was reversed in the complementation mutant of HHP1 expressing the HHP1 gene. The data suggest that the mutation of HHP1 renders plants hypersensitive to ABA and osmotic stress and HHP1 might be a negative regulator in ABA and osmotic signalling

EFFECTS OF UPPER EXTREMITY FATIGUE ON BASKETBALL SHOOTING ACCURACY

The purpose of this study was to investigate the effect of upper extremity fatigue on basketball shooting accuracy. Twenty-four elite male basketball players from 2 teams the top 3 Taiwan High Schools were chosen as subjects. After a warm-up and proper practice, they were asked to shoot from 3 varied distance positions before and after fatigue protocols. The protocols used were the chest press and wrist curls. Results show that the shooting accuracies in different distance positions declined significantly after the chess press protocol, however, there was no significant difference in shooting accuracy after doing the wrist-curls protocol. The results suggested that avoiding shoulder muscle fatigue should keep the shooting accuracy constant and in return helping them win a basketball game

Family Variables and Reading

others of poor and average readers in Japan, Taiwan and the United States were iterviewed about their child-rearing practices, attitudes, and beliefs, and their children's current and earlier experiences. Poor readers represented the lowest fifth percentile in reading scores; they were matched by classroom, sex, and age with average readers; i.e., children who obtained reading scores within one standard deviation from the mean. The groups seldom differed significantly according to environmental variables and parent-child interactions. Maternal ratings of cognitive and achievement variables differentiated both the children in the two groups and the mothers themselves. Maternal beliefs and descriptions of how children use time also differed between the two groups. Notable was the absence of significant interactions between country and reading level.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68579/2/10.1177_002221948401700305.pd

極端水文事件土砂量對陳有蘭溪河川型態演變影響分析

The total sediment yield from the 1999 Chichi earthquake to Typhoon Morakot in 2009 in the Chenyoulan River watershed is around 158.1×106 m3. The excess sediment yield has resulted in serious sediment deposition, widening river width and river meandering in the Chenyoulan River. By comparison of DEMs from 2004 and 2010, sediment deposits are obvious at the convergences of the tributaries and the in main river. Especially apparent are the deposited depth of 2.9 m at the convergence of the Junkeng River and the main river and the deposited depth of 2.6 m at the convergence of the Shibachong River and the main river. The serious sediment deposition has also resulted in river meandering and serious scouring upstream from the convergence of the Shibachong River and the main river, and widening river width and scouring in the main channel downstream from the convergence of the Shibachong River and the main river.陳有蘭溪集水區由1999 年集集地震至2009 年莫拉克颱風約產生158.1×106 m3 土砂量，巨量土砂產出在主河段造成河段淤積、拓寬及擺盪；以2004 年及2010 年DEM 比較結果，支流匯入溪處是主要土砂堆積處，又以郡坑溪匯入處之淤積2.9 m 及十八重溪匯入處之淤積2.6m 為最；受土砂淤積影響，在十八重溪上游匯入處上游河段以河道擺盪及河岸淘刷為主，在十八重溪匯入處下游河段則以河道拓寬及主深槽刷深為主

Prevalence of latent tuberculosis infection in BCG-vaccinated healthcare workers by using an interferon-gamma release assay and the tuberculin skin test in an intermediate tuberculosis burden country

BackgroundThe risk of healthcare workers (HCWs) acquiring tuberculosis (TB) infection is high. We determined the prevalence of latent TB infection (LTBI) in HCWs with a high Bacille Calmette-Guérin (BCG) vaccine coverage in an intermediate TB burden country by using an interferon-gamma release assay [QuantiFERON-TB Gold (QFT-G)] and by using the tuberculin skin test (TST). Risk factors associated with a positive test were determined.MethodsThis prospective cross-sectional study enrolled HCWs from a medical center in Taiwan. Participants were grouped into workers without exposure (Group 1) and workers who self-reported a history of TB exposure (Group 2). All participants completed a questionnaire to collect demographic information and risk factors for acquiring TB. The QFT-G test and the TST were administered and risk factors for a positive test were analyzed.ResultsWe recruited 193 HCWs [149 (77.2%) female workers] with a mean age of 35.6 years. All were BCG-vaccinated. The prevalence of LTBI was 88.8% (based on the TST) and 14.5% (based on the QFT-G test). There was no difference between HCWs with and without known exposure to TB. Agreement between the tests was poor (i.e., the kappa value was less than 0.05). Multivariable logistic regression showed that only the QFT-G test was associated with age (35 years or greater) (adjusted OR, 2.53; p = 0.03).ConclusionBy using the QFT-G test or TST, this study found a similar prevalence of LTBI in HCWs with and without known exposure to TB. This suggests that in intermediate TB burden countries exposure to TB may occur within the hospital and within the community. Compared to the TST, the QFT-G test was correlated better with age, which is a known risk factor for latent TB infection

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes

Thioredoxin 1 (Trx1) is a 12-kDa oxidoreductase that catalyzes thiol-disulfide exchange reactions to reduce proteins with disulfide bonds. As such, Trx1 helps protect the heart against stresses, such as ischemia and pressure overload. Mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that regulates cell growth, metabolism, and survival. We have shown previously that mTOR activity is increased in response to myocardial ischemia-reperfusion injury. However, whether Trx1 interacts with mTOR to preserve heart function remains unknown. Using a substrate-trapping mutant of Trx1 (Trx1C35S), we show here that mTOR is a direct interacting partner of Trx1 in the heart. In response to H2O2 treatment in cardiomyocytes, mTOR exhibited a high molecular weight shift in non-reducing SDS-PAGE in a 2-mercaptoethanol-sensitive manner, suggesting that mTOR is oxidized and forms disulfide bonds with itself or other proteins. The mTOR oxidation was accompanied by reduced phosphorylation of endogenous substrates, such as S6 kinase (S6K) and 4E-binding protein 1 (4E-BP1) in cardiomyocytes. Immune complex kinase assays disclosed that H2O2 treatment diminished mTOR kinase activity, indicating that mTOR is inhibited by oxidation. Of note, Trx1 overexpression attenuated both H2O2-mediated mTOR oxidation and inhibition, whereas Trx1 knockdown increased mTOR oxidation and inhibition. Moreover, Trx1 normalized H2O2-induced down-regulation of metabolic genes and stimulation of cell death, and an mTOR inhibitor abolished Trx1-mediated rescue of gene expression. H2O2-induced oxidation and inhibition of mTOR were attenuated when Cys-1483 of mTOR was mutated to phenylalanine. These results suggest that Trx1 protects cardiomyocytes against stress by reducing mTOR at Cys-1483, thereby preserving the activity of mTOR and inhibiting cell death